Estimulação Magnética Transcraniana e o seu Papel na Reestruturação dos Serviços de Saúde Mental

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Xylem Transcription Profiles Indicate Potential Metabolic Responses For Economically Relevant Characteristics Of Eucalyptus Species.

Eucalyptus is one of the most important sources of industrial cellulose. Three species of this botanical group are intensively used in breeding programs: E. globulus, E. grandis and E. urophylla. E. globulus is adapted to subtropical/temperate areas and is considered a source of high-quality cellulose; E. grandis grows rapidly and is adapted to tropical/subtropical climates; and E. urophylla, though less productive, is considered a source of genes related to robustness. Wood, or secondary xylem, results from cambium vascular differentiation and is mostly composed of cellulose, lignin and hemicelluloses. In this study, the xylem transcriptomes of the three Eucalyptus species were investigated in order to provide insights on the particularities presented by each of these species. Data analysis showed that (1) most Eucalyptus genes are expressed in xylem; (2) most genes expressed in species-specific way constitutes genes with unknown functions and are interesting targets for future studies; (3) relevant differences were observed in the phenylpropanoid pathway: E. grandis xylem presents higher expression of genes involved in lignin formation whereas E. urophylla seems to deviates the pathway towards flavonoid formation; (4) stress-related genes are considerably more expressed in E. urophylla, suggesting that these genes may contribute to its robustness. The comparison of these three transcriptomes indicates the molecular signatures underlying some of their distinct wood characteristics. This information may contribute to the understanding of xylogenesis, thus increasing the potential of genetic engineering approaches aiming at the improvement of Eucalyptus forest plantations productivity.1420

CARACTERÍSTICAS CLÍNICAS E DEMOGRÁFICAS DE PACIENTES SUBMETIDOS À REVASCULARIZAÇÃO DO MIOCÁRDIO EM UM HOSPITAL UNIVERSITÁRIO / DEMOGRAPHIC AND CLINICAL CHARACTERISTICS OF PATIENTS UNDERGOING CORONARY ARTERY BYPASS GRAFT IN A UNIVERSITARY HOSPITAL

Introdução: A avaliação pré-operatória da revascularização do miocárdio, com identificação de características clínicas e demográficas associadas aos fatores de risco cirúrgico e o desenvolvimento de medidas capazes de reduzi-los, reflete na diminuição da morbimortalidade. Objetivo: Identificar o perfil clínico e demográfico dos pacientes submetidos à cirurgia de revascularização do miocárdio. Métodos: Os dados foram obtidos por meio das fichas de evolução fisioterapêutica de 121 pacientes submetidos à cirurgia de revascularização do miocárdio no Hospital Universitário Presidente Dutra, São Luís (MA), no período de janeiro de 2011 a fevereiro de 2012. Resultados: A idade média dos pacientes foi 60,7 ± 9,1 anos, com predominância de idosos (53,7%), do sexo masculino (71,1%), procedentes de municípios do interior do Estado do Maranhão (57,9%) e com sobrepeso (44,6%). A hipertensão arterial sistêmica foi a comorbidade mais prevalente (76,9%), seguida por diabetes mellitus (46,3%) e tabagismo (31,4%). Conclusão: A maioria dos pacientes submetidos à cirurgia de revascularização do miocárdio foram homens, idosos, procedentes do interior do Estado, com fatores de risco clássicos para cardiopatia isquêmica. O conhecimento do perfil clínico e demográfico é importante para o planejamento de cuidados pós-operatórios pela equipe multiprofissional, visto que pacientes com risco aumentado de complicações podem ser beneficiados pela assistência fisioterapêutica no período pré-operatório.Palavras-chave: Perfil epidemiológico. Comorbidade. Coronariopatia. Cirurgia Cardíaca.AbstractIntroduction: The preoperative evaluation of myocardial revascularization with identification of clinical and demographic characteristics associated with surgical risk factors, as well as the development of measures that are able to reduce them may reflect in decreased morbidity and mortality. Objective: To identify clinical and demographic profile of patients undergoing coronary artery bypass graft. Methods: Data were obtained from Physical Therapy evolution forms of one hundred twenty-one patients undergoing coronary artery bypass graft at the University Hospital Presidente Dutra, from January 2011 to February 2012. Results: The mean age of patients was 60.7 ± 9.1 years old and predominance of elderly people (53.7%). Most individuals were males (71.1%), lived in the countryside (57.9%) and overweight (44.6%). Hypertension was the most prevalent comorbidity (76.9%), followed by diabetes mellitus (46.3%). Conclusion: Patients undergoing coronary artery bypass graft are mostly men. Most individuals were males living in the countryside and being overweight as well as having classical risk factors for ischemic heart disease. Thus, knowing the clinical and demographic profiles of these patients may assist in planning postoperative care by the multidisciplinary team, whereas patients with increased risk of complications may benefit from physical therapy assistance in the preoperative period.Keywords: Health profile. Comorbidity. Coronary disease. Cardiac surgery

Xylem transcription profiles indicate potential metabolic responses for economically relevant characteristics of Eucalyptus species

Abstract Background Eucalyptus is one of the most important sources of industrial cellulose. Three species of this botanical group are intensively used in breeding programs: E. globulus, E. grandis and E. urophylla. E. globulus is adapted to subtropical/temperate areas and is considered a source of high-quality cellulose; E. grandis grows rapidly and is adapted to tropical/subtropical climates; and E. urophylla, though less productive, is considered a source of genes related to robustness. Wood, or secondary xylem, results from cambium vascular differentiation and is mostly composed of cellulose, lignin and hemicelluloses. In this study, the xylem transcriptomes of the three Eucalyptus species were investigated in order to provide insights on the particularities presented by each of these species. Results Data analysis showed that (1) most Eucalyptus genes are expressed in xylem; (2) most genes expressed in species-specific way constitutes genes with unknown functions and are interesting targets for future studies; (3) relevant differences were observed in the phenylpropanoid pathway: E. grandis xylem presents higher expression of genes involved in lignin formation whereas E. urophylla seems to deviates the pathway towards flavonoid formation; (4) stress-related genes are considerably more expressed in E. urophylla, suggesting that these genes may contribute to its robustness. Conclusions The comparison of these three transcriptomes indicates the molecular signatures underlying some of their distinct wood characteristics. This information may contribute to the understanding of xylogenesis, thus increasing the potential of genetic engineering approaches aiming at the improvement of Eucalyptus forest plantations productivity